Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC114H206N32O22

DescriptionStandard

        PKKKRKVALWKTLLKKVLKA
    

Molecular Weight2377.06 Da

Isoelectric Point (pI)11.51

Net Charge (pH 7.0)8.95

Net Charge (pH 7.4) 8.88

Charge Density (pH 7.0) 0.4475

GRAVY Index-0.58

Hydrophobic Moment 0.66

Boman Index-0.30

Instability Index20.66

Aliphatic Index 117.00

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 908.31

LogP -3.03

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 88.0

Heavy Atoms 168.0

Ring Count 3.0

Amide Bonds 19.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0408114 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagii [Animal]

FamilyDermaseptin

Tax ID8395

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorophore labeling

C-TermAmidation

Other ModsN-term detail: Labelled rhodamine

Bio-Activity Profile

Function

Cell-penetrating peptide Antimicrobial

TargetHeLa

MethodFluorescence-based uptake assay

FIRST PREV 1 2

Showing 1 records on this page Ã‚Â· Page 2 of 2