Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC336H528N98O104S2

DescriptionStandard

        QHWSYGLRPGGKREVESLQESYAEVPNEVSFTELQHLECSIPQNRISLVRDALMNWLEGENARKKI
    

Molecular Weight7668.51 Da

Isoelectric Point (pI)5.61

Net Charge (pH 7.0)-2.05

Net Charge (pH 7.4) -2.40

Charge Density (pH 7.0) -0.0311

GRAVY Index-0.76

Hydrophobic Moment 0.53

Boman Index-0.13

Instability Index54.55

Aliphatic Index 81.21

Aromaticity 0.0758

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3304.74

LogP -32.84

H-bond Donors 114.0

H-bond Acceptors 106.0

Rotatable Bonds 258.0

Heavy Atoms 540.0

Ring Count 12.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094063 VERIFIED: YES

Provenance & Taxonomy

OrganismAquarana catesbeiana [Animal]

FamilyProgonadoliberin

Tax ID8400

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour