Peptide Database

Peptide NameCART(55-102)

Function Ontology

Cardiovascular

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC217H357N63O63S6

DescriptionStandard

        IPIYEKKYGQVPMCDAGEQCAVRKGARIGKLCDCPRGTSCNSFLLK
    

Molecular Weight5048.93 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.42

Charge Density (pH 7.0) 0.0807

GRAVY Index-0.29

Hydrophobic Moment 0.76

Boman Index-0.07

Instability Index12.58

Aliphatic Index 70.00

Aromaticity 0.0652

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2041.87

LogP -21.03

H-bond Donors 75.0

H-bond Acceptors 73.0

Rotatable Bonds 169.0

Heavy Atoms 349.0

Ring Count 6.0

Amide Bonds 48.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028357 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCART(55-102)

Tax ID9823

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide14-32; 20-40

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory Feeding regulator

Half-LifeMammalian: 20 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0395833 VERIFIED: NO