Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC878H1401N247O229S5

DescriptionStandard

        PTALPTAQEPMLLLAVTEFVANSAAFTYFAAGVLRKNISSDMLPRRFPLQLRTKSMGLFSPQLQQHYPDHPMELHLSARRQPLLSCHPDALHGAFFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVSLKGPLRRPRAGLRGLPVPQVKRLETLLKFGLWLFGVP
    

Molecular Weight19241.36 Da

Isoelectric Point (pI)11.11

Net Charge (pH 7.0)11.39

Net Charge (pH 7.4) 11.05

Charge Density (pH 7.0) 0.0651

GRAVY Index0.04

Hydrophobic Moment 0.68

Boman Index0.09

Instability Index60.32

Aliphatic Index 97.03

Aromaticity 0.0800

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7486.14

LogP -79.21

H-bond Donors 258.0

H-bond Acceptors 250.0

Rotatable Bonds 612.0

Heavy Atoms 1359.0

Ring Count 38.0

Amide Bonds 187.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0206741 VERIFIED: NO

Provenance & Taxonomy

OrganismCircaetus pectoralis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria