Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC189H312N48O61S3

DescriptionStandard

        MAKQQMNLVEIEVMNSLQELTLEELDNVLGAGSGIIHFI
    

Molecular Weight4328.98 Da

Isoelectric Point (pI)4.14

Net Charge (pH 7.0)-5.40

Net Charge (pH 7.4) -5.67

Charge Density (pH 7.0) -0.1384

GRAVY Index0.33

Hydrophobic Moment 0.40

Boman Index0.23

Instability Index57.92

Aliphatic Index 127.44

Aromaticity 0.0256

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1766.85

LogP -14.63

H-bond Donors 57.0

H-bond Acceptors 60.0

Rotatable Bonds 152.0

Heavy Atoms 301.0

Ring Count 2.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105046 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus mitis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

RECORD: Rec_0404076 VERIFIED: NO