Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1155H1781N269O343S8

DescriptionStandard

        QIDDLAEVDYSLRSLPAVFQPFIDLDLKGVVFPAGNYTGSPDIAASFTIPDQSDAMLYLAFPEHFFQTSSFAYYTAGAFNMTIAEETCSYFNLNTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLQQDSFTVEIQGSMEVLAILPDSTTQSLFTLNIAANNSISLNIFDQKLMGSLCLNRIQFSLAHSNVGSFEVLLLKNILSYILQTEVIPLANAKLSKGFPLP
    

Molecular Weight25179.61 Da

Isoelectric Point (pI)4.26

Net Charge (pH 7.0)-13.06

Net Charge (pH 7.4) -13.44

Charge Density (pH 7.0) -0.0570

GRAVY Index0.34

Hydrophobic Moment 0.60

Boman Index0.25

Instability Index44.87

Aliphatic Index 104.80

Aromaticity 0.1135

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091102 VERIFIED: NO

Provenance & Taxonomy

OrganismBombycilla garrulus (Bohemian waxwing) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria