Peptide Database

Peptide NameSLAY-screened peptide P2959

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC108H167N27O31S2

DescriptionStandard

        LTYFYTLCTSFRSRITQCVT
    

Molecular Weight2403.77 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0869

GRAVY Index0.34

Hydrophobic Moment 0.41

Boman Index0.08

Instability Index53.90

Aliphatic Index 73.00

Aromaticity 0.2000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 965.18

LogP -9.67

H-bond Donors 39.0

H-bond Acceptors 35.0

Rotatable Bonds 74.0

Heavy Atoms 168.0

Ring Count 4.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220660 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/