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MYP_097034
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Basic Information
Chrysophsin-1 (fish, chordates, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C136H211N45O26
Standard
Sequence
FFGWLIKGAIHAGKAIHGLIHRRRH
Physicochemical Analysis
2892.42 Da
12.00
5.11
4.70
0.2043
0.00
0.56
0.10
70.08
105.60
0.1200
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1129.97
-5.98
42.0
35.0
95.0
207.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0289542 VERIFIED: YES
Provenance & Taxonomy
Red sea bream [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
highly hemolytic
~1 μM
HC50
PaperPurification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major.
RECORD: Rec_0299100 VERIFIED: YES
Provenance & Taxonomy
Red sea bream [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
A. salmonicida NCMB 1102
10 μM
MIC
PaperPurification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major.
RECORD: Rec_0313735 VERIFIED: YES
Provenance & Taxonomy
Pagrus major [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
V. harveyi (Gram-negative)
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0318778 VERIFIED: YES
Provenance & Taxonomy
Pagrus major [Animal]
Red sea bream,Chrysophrys majororPagrus major
143350
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
Breast Cancer (Not Available)
PMID12581207;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0352361 VERIFIED: YES
Provenance & Taxonomy
Chrysophrys major [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
vulnificus ATCC 33148
5 μM
MIC
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
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