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MYP_097034
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Basic Information
Chrysophsin-1 (fish, chordates, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C136H211N45O26
Standard
Sequence
FFGWLIKGAIHAGKAIHGLIHRRRH
Physicochemical Analysis
2892.42 Da
12.00
5.11
4.70
0.2043
0.00
0.56
0.10
70.08
105.60
0.1200
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1129.97
-5.98
42.0
35.0
95.0
207.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0259355 VERIFIED: YES
Provenance & Taxonomy
Pagrus major [Animal]
Chrysophsin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Breast cancer (cell line not reported)
PaperCancerPPD2 curated year-page record; primary PMID 12581207 (2003), additional curated PMID 18957441. PMID12581207;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0262168 VERIFIED: NO
Provenance & Taxonomy
Red sea [Animal]; Actinopterygii [Animal]
Chrysophsin
33208; 7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0264536 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12581207/ PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0282326 VERIFIED: YES
Provenance & Taxonomy
Red sea bream [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
V. anguillarum ATCC 19264
2.5 μM
MIC
PaperPurification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major.
RECORD: Rec_0286209 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial Toxic Antimicrobial Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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