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MYP_097034
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Basic Information
Chrysophsin-1 (fish, chordates, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C136H211N45O26
Standard
Sequence
FFGWLIKGAIHAGKAIHGLIHRRRH
Physicochemical Analysis
2892.42 Da
12.00
5.11
4.70
0.2043
0.00
0.56
0.10
70.08
105.60
0.1200
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1129.97
-5.98
42.0
35.0
95.0
207.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0198562 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0201269 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
1 μM
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/18052076/ PMID18052076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18052076/
RECORD: Rec_0212653 VERIFIED: YES
Provenance & Taxonomy
Actinopterygii [Animal]
7898;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Streptococcus mutans Clarke UA159 / ATCC 700610
5.535, 32 μM
Confocal microscopy-fluorescence
RECORD: Rec_0224672 VERIFIED: YES
Provenance & Taxonomy
Chrysophrys major [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0229326 VERIFIED: YES
Provenance & Taxonomy
Chrysophrys major [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Aeromonas salmonicida NCMB 1102
10 μM
MIC
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
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