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MYP_097017
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Basic Information
Vif (30-65)
Antimicrobial
Antiviral
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Standard
36 amino acids
C193H286N58O50
Standard
Sequence
YVSGKARGWFYRHHYESPHPRISSEVHIPLGDARLV
Physicochemical Analysis
4218.69 Da
9.52
2.11
1.70
0.0587
-0.66
0.38
-0.07
65.02
73.06
0.1389
9970.00
9970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1713.09
-14.00
62.0
56.0
129.0
301.0
13.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021340 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Protease inhibition Antiviral
HIV-1 protease
20-30 %
Protease activity at 1 μM peptide
PMID10074409 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10074409/
RECORD: Rec_0065235 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Protease inhibition
Hut-78
75 %
Inhibition
PaperHuman immunodeficiency virus type 1 Vif-derived peptides inhibit the viral protease and arrest virus production. PMID9891983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9891983/
RECORD: Rec_0077053 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 11.1%, E 33.3%, T 36.1%, C 19.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
RECORD: Rec_0111768 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Protease inhibition Antiviral
Rous sarcoma virus protease
80-90 %
Protease activity at 1 μM peptide
PMID10074409 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10074409/
RECORD: Rec_0300269 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Protease inhibition
75.1 %
Inhibition
PaperPeptides derived from HIV-1 Vif: a non-substrate based novel type of HIV-1 protease inhibitors. PMID10074409 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10074409/