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MYP_097007
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Basic Information
TAT-RasGAP317-326
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
22 amino acids
C119H201N49O29S
Standard
Sequence
RRRQRRKKRGGGDTRLNTVWMW
Physicochemical Analysis
2814.25 Da
12.00
7.76
7.55
0.3527
-2.01
0.50
-0.80
118.66
30.91
0.0909
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1355.28
-15.15
53.0
38.0
98.0
198.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0182402 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Retro-inverso all-D peptide
Bio-Activity Profile
Antibacterial Antimicrobial Antibiofilm Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PA14
32 μg/mL
MIC
PMID33852935 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33852935/
RECORD: Rec_0205624 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
None
Retro-inverso all-D peptide
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID28638371 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28638371/
RECORD: Rec_0240636 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Retro-inverso all-D peptide
Bio-Activity Profile
Cytotoxic Anticancer Tumor chemosensitization
tumor cell lines
Tumor-cell sensitization and cell-death assay
PaperTAT-RasGAP317-326 requires p53 and PUMA to sensitize tumor cells to genotoxins PMID17510315
RECORD: Rec_0254000 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Retro-inverso all-D peptide
Bio-Activity Profile
Antibacterial Antimicrobial Antibiofilm Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
128 μg/mL
MIC
PMID33852935 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33852935/
RECORD: Rec_0305896 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Retro-inverso all-D peptide
Bio-Activity Profile
Antibacterial Antimicrobial Anticancer
Enterococcus faecium
23 μM
MIC
PaperThe Anticancer Peptide TAT-RasGAP317-326 Exerts Broad Antimicrobial Activity. PMID28638371
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