Peptide Database

Peptide NameColicin-Ia

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length659 amino acids

Chemical FormulaC3307H5230N880O1004S13

DescriptionStandard

        MSSEISYYDNEGNPHNSDGEFLLIIESGPKDINGGYPMTEIPLGNTQGLTFPHPDFTIMTDMFTQWWGDAGLDQRKTQRPQPYVPKTTMPNKVNAENGINDGIYKVELDNRKVIDVYVDKTGRGSLKDSNLDENTKNSVISRAETLFRELYNSKNHAQPLDDKNHTQYIYQDEKGDIKTTTDVSIAKPYLKNNNGYFKGISFNNVYNTIRWSLFIDNLKRKGIKTIPMRTNFDKIHVTKQVIEYVEKNVRESIDVLRDHSHDIKNNLVPSIKIAELNEFPANTVGKYDTQISNTLFASNFLTQKIAHSDLIKMAKNNESISVTARVALVPDVKNNKIDVNLVKADGVLISDKVRVVEVQYNNKTGIYGTLVKDSNFQMALTTERGFSSAGLVFWPAAASLDKDPALVPGRVTIPQSITKTSLEAPYPHQINDAILVFPEKSGLLPVYVYSSYARTRYLDEKDNRTEQEKAFEDIKSAVKFTADFYKDVFEHYGDKAEKIAQSMAKEAKNKKLTTPQNAEKLYNKHKSNLDKKIKAADRAIIAEHIKSLTLKSSSDNLKIAANNLKIFSKGMKFTSLAIDGYDLLVTELSKAIETGNWRPFYVKAETIIAGMAASAVVGFAFSVLLATPYGIIAYGLIMAGIGAMVDEKLIEDINKLLGV
    

Molecular Weight73797.04 Da

Isoelectric Point (pI)8.37

Net Charge (pH 7.0)3.60

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0055

GRAVY Index-0.41

Hydrophobic Moment 0.75

Boman Index-0.02

Instability Index23.55

Aliphatic Index 87.16

Aromaticity 0.0880

Extinction Coeff. Reduced 69220.00

Extinction Coeff. Oxidized 69220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0277868 VERIFIED: YES

Provenance & Taxonomy

OrganismPectobacterium carotovorum [Bacterium]

FamilyChannel forming colicin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli