Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC358H595N99O93S9

DescriptionStandard

        MKLFLVLIILQFEVPTDTARPRKCFSNITGYCRKKCEMGEIYEMACLNGKLCCVNVLELRARRKIAKPPP
    

Molecular Weight8062.75 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)6.45

Net Charge (pH 7.4) 6.12

Charge Density (pH 7.0) 0.0921

GRAVY Index0.03

Hydrophobic Moment 0.60

Boman Index-0.03

Instability Index40.99

Aliphatic Index 94.71

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3098.35

LogP -22.65

H-bond Donors 113.0

H-bond Acceptors 109.0

Rotatable Bonds 271.0

Heavy Atoms 559.0

Ring Count 10.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121302 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0252846 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin