Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC527H832N140O152S4

DescriptionStandard

        FFKHFFSSFSLSCSRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDGGRGTVHISKVFVTAIFSTPLDNAGPTSVALTSCRTSPGDVDIKLNGKT
    

Molecular Weight11689.35 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)4.00

Net Charge (pH 7.4) 3.61

Charge Density (pH 7.0) 0.0367

GRAVY Index0.26

Hydrophobic Moment 0.59

Boman Index0.18

Instability Index24.24

Aliphatic Index 91.19

Aromaticity 0.0917

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4628.51

LogP -50.04

H-bond Donors 166.0

H-bond Acceptors 163.0

Rotatable Bonds 378.0

Heavy Atoms 823.0

Ring Count 20.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118315 VERIFIED: NO

Provenance & Taxonomy

OrganismCalcarius ornatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria