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MYP_096886
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Basic Information
P6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C123H201N39O20
Standard
Sequence
YIRKIRRFFKKRFKFRKK
Physicochemical Analysis
2546.16 Da
12.00
10.75
10.54
0.5974
-1.50
1.01
-0.77
37.96
43.33
0.2778
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1043.87
-4.26
41.0
31.0
93.0
182.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0066874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. sangui ATCC 10556
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0114527 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. mutans ATCC UA159
16 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0163763 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Murine blood [HC10 = >640 microg/mL, HC50 = >640 microg/mL, Percent Hemolysis ± SD Hmax (100%) = 8.21 ± 1.2]
640 μg/mL
HC50
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0267507 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
MRSA 18466
32 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0356558 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus ATCC 25923
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
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