Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2464H3916N618O703S22

DescriptionStandard

        MKSCVLFFFFFYLASPISSITAPPPPGIKLQIRENAKDVLKDLGLMYLKGLVNKQFPIDDICLPIKSVNLTDLQVDPAKVDFKFQENIGVQIEIKDMNFSLEIQREAKVPFTQIKIIEGTTTLTAEGVTATITVRMNQNPQGHLNVEIPRDNCTIKADTIRTTSSGLTGFLLDSLQYFRLYLYLFNDKICPALQPMINNKLKDLPMMSTVYEDHQLDLDYSLSSDIEVTSSSLDISFKGLLSVHGKAVDPGSIRPGREPVFTETNKMVYVGISEFFFNGAAMAIYKSGPFEFNVPEMEGLLVGLGQKIMEIKPGPWTAELIEAPIIEISNDDLSATAYFKAQRKAKLNGFLMTCRFKMDIEFKERLLIMNIQEPKCKEKAGKIKGKFLVRRQCSNRFTSISLYQQIFIIIIIIIIITCVSLFVQAFLVNVFHERITKSLVKEIPIPLPAELSLINATNQFEEGYLVVGGSLTFNPQNSSNAGG
    

Molecular Weight54150.60 Da

Isoelectric Point (pI)6.49

Net Charge (pH 7.0)-1.17

Net Charge (pH 7.4) -1.84

Charge Density (pH 7.0) -0.0024

GRAVY Index0.08

Hydrophobic Moment 0.75

Boman Index0.12

Instability Index33.82

Aliphatic Index 101.72

Aromaticity 0.0932

Extinction Coeff. Reduced 23380.00

Extinction Coeff. Oxidized 23880.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016631 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus (Not founde tilapia) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria