Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length495 amino acids

Chemical FormulaC2532H3974N656O711S24

DescriptionStandard

        MTSWKGCQRQYTLVQNAPGAQGHPKIRMSQKMWIRLMLMAAMAVALKGRKIPGIVLRISQKGLDHVSKQGAELLQEELLKISLPIQMGLGDYEFIRMMISKFMLQKSHISVVSKGFVLSMTNSSIIINGKWTSQKSKNNHVPFDLKLDDVTIRTGFNLGKNNNNQISISVSSCIIHIGSVHIFTSTNQSLLREVYQNDIQTTLHNNVFQKICSVIRTSTTSYVEPYLHTMPVKVNLDGIAGIDYSLIQPPKSRGYHLDIPLKGQFFSLTHHTSFPFSPSAVSFRSSQLQMVYFGVSHSFFDSAIHVYKNAGIKSLQTNSSMVPKDSKYTLSTDYYGILIPQLSKDFPSMAMTIDIDFPSSAPTIFVDSRMKLSLMSSLSTHVFVVFSNSSQTPLFTLKLKTTVTLYIAVKDGTILGRMTLESLSMELKKSYIGHFQASLLQDPFTYYMSKVWLPIINGRLEQGYPLPVPANLHFSDYIVYPHKHFLVFGTDFIYS
    

Molecular Weight55750.17 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)19.03

Net Charge (pH 7.4) 17.76

Charge Density (pH 7.0) 0.0385

GRAVY Index-0.01

Hydrophobic Moment 0.74

Boman Index0.11

Instability Index35.92

Aliphatic Index 92.89

Aromaticity 0.1030

Extinction Coeff. Reduced 51800.00

Extinction Coeff. Oxidized 51925.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417117 VERIFIED: NO

Provenance & Taxonomy

OrganismPhascolarctos cinereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria