Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC368H593N99O96S8

DescriptionStandard

        MRVLYSILGALALLSVVPQARTFFLKDTCSLEYLNCRMKCNPDEQAIKYCADWTICCKAKNTKFKRKKKW
    

Molecular Weight8196.77 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)8.44

Net Charge (pH 7.4) 8.11

Charge Density (pH 7.0) 0.1205

GRAVY Index-0.17

Hydrophobic Moment 0.54

Boman Index-0.07

Instability Index11.80

Aliphatic Index 82.29

Aromaticity 0.1143

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3197.27

LogP -24.65

H-bond Donors 119.0

H-bond Acceptors 113.0

Rotatable Bonds 277.0

Heavy Atoms 571.0

Ring Count 12.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415556 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin