Peptide Database

Peptide NameMotilin(1–12)ghrelin(10–28)

Function Ontology

Gastrointestinal bioactivity ▸ Gastrointestinal motility

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC170H278N52O44

DescriptionStandard

        FVPIFTYGELQRQRVQQRKESKKPPAKLQPR
    

Molecular Weight3754.35 Da

Isoelectric Point (pI)11.05

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.1858

GRAVY Index-1.28

Hydrophobic Moment 0.39

Boman Index-0.39

Instability Index61.43

Aliphatic Index 59.68

Aromaticity 0.0968

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1603.58

LogP -14.50

H-bond Donors 54.0

H-bond Acceptors 50.0

Rotatable Bonds 126.0

Heavy Atoms 266.0

Ring Count 7.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225956 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyMotilin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Gastrointestinal motility

TargetGPR38 agonist activity

Activity0.01-0.01 μM

MethodEC50

Half-LifeIntravenouly injected in Sprague-Dawley rats, in vivo; 534 s

RECORD: Rec_0284790 VERIFIED: YES