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MYP_096842
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Basic Information
CPF-12 (Derived from CPF-C1)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C89H137N21O14
Standard
Sequence
LLWKALRLWWKVL
Physicochemical Analysis
1725.17 Da
11.17
2.76
2.55
0.2122
0.77
0.69
0.30
53.95
180.00
0.2308
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
573.83
3.82
22.0
17.0
54.0
124.0
6.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0235471 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
64
MIC
PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0243481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii 2982
16
MIC
PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0249018 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcuss aureus ATCC 25923
16 μg/mL
MIC
PaperNovel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria. Chem Biol Drug Des. 2017 Nov;90(5):690-702. doi: 10.1111/cbdd.12988. PMID: 28371431. PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0252261 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii 1980
16
MIC
PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0268610 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii 4956
16 μg/mL
MIC
PaperNovel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria. Chem Biol Drug Des. 2017 Nov;90(5):690-702. doi: 10.1111/cbdd.12988. PMID: 28371431. PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
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