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MYP_096824
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Basic Information
Defensin MGD-1 (molluscas, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
38 amino acids
C181H270N64O47S8
Standard
Sequence
GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLRCTCYRC
Physicochemical Analysis
4351.00 Da
9.12
5.94
5.46
0.1563
-0.73
0.48
-0.18
48.65
20.53
0.1316
9970.00
10470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1790.21
-22.16
73.0
64.0
134.0
300.0
11.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0173062 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
29158
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperEur. J. Biochem. 240:302-306(1996) | http://www.ncbi.nlm.nih.gov/pubmed/8925841 PMID8925841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8925841/
RECORD: Rec_0183835 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-25, 10-33, 14-35, 21-38, 25-33, 4-25, 10-33, 14-35
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
6.2 μM
MBC
PMID10564642;8925841;11087396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10564642/
RECORD: Rec_0184864 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-25, 10-33, 14-35, 21-38, 25-33, 4-25, 10-33, 14-35
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli D31
1.2 μM
MBC
PMID10564642;8925841;11087396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10564642/
RECORD: Rec_0199845 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
29158
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
No hemolytic activity
Hemolysis
PMID8925841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8925841/
RECORD: Rec_0219787 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-25, 10-33, 14-35, 21-38, 25-33, 4-25, 10-33, 14-35
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio metshnikovii
100 μM
MBC
PMID10564642;8925841;11087396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10564642/
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