Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC49H78N14O14

DescriptionStandard

        LPQQQAQFK
    

Molecular Weight1087.23 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0843

GRAVY Index-1.23

Hydrophobic Moment 0.18

Boman Index-0.21

Instability Index69.41

Aliphatic Index 54.44

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 485.71

LogP -4.72

H-bond Donors 14.0

H-bond Acceptors 15.0

Rotatable Bonds 36.0

Heavy Atoms 77.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0255434 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV inhibitory Antidiabetic

TargetACE; DPP-IV

PaperIdentification of in vitro angiotensin-converting enzyme and dipeptidyl peptidase IV inhibitory peptides from draft beer by virtual screening and molecular docking. Journal of the Science of Food and Agriculture 102:1085-1094 (2022). PMID: 34309842. PMID34309842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34309842/

RECORD: Rec_0372368 VERIFIED: YES