Peptide Database

Peptide NameRibonuclease K6 (RNase K6) (EC 3.1.27.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC784H1213N219O222S13

DescriptionStandard

        MVVDLPRYLPLLLLLELWEPMYLLCSQPKGLSRAHWFEIQHIQTSRQPCNTAMRGVNNYTQHCKQINTFLHESFQNVAATCSLHNITCKNGRKNCHESAEPVKMTDCSHTGGAYPNCRYSSDKQYKFFIVACEHPKKEDPPYQLVPVHLDKIV
    

Molecular Weight17675.20 Da

Isoelectric Point (pI)8.37

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.36

Charge Density (pH 7.0) 0.0210

GRAVY Index-0.45

Hydrophobic Moment 0.62

Boman Index-0.03

Instability Index41.65

Aliphatic Index 75.16

Aromaticity 0.0915

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7057.17

LogP -66.40

H-bond Donors 246.0

H-bond Acceptors 247.0

Rotatable Bonds 572.0

Heavy Atoms 1238.0

Ring Count 36.0

Amide Bonds 170.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329922 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyPancreatic ribonuclease

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic

TargetS. saprophyticus (Gram-positive)

RECORD: Rec_0377954 VERIFIED: YES