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MYP_096776
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Basic Information
Ribonuclease K6 (RNase K6) (EC 3.1.27.-)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Enzyme / Catalytic activity ▸ Hydrolase
Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
153 amino acids
C784H1213N219O222S13
Standard
Sequence
MVVDLPRYLPLLLLLELWEPMYLLCSQPKGLSRAHWFEIQHIQTSRQPCNTAMRGVNNYTQHCKQINTFLHESFQNVAATCSLHNITCKNGRKNCHESAEPVKMTDCSHTGGAYPNCRYSSDKQYKFFIVACEHPKKEDPPYQLVPVHLDKIV
Physicochemical Analysis
17675.20 Da
8.37
3.21
2.36
0.0210
-0.45
0.62
-0.03
41.65
75.16
0.0915
21430.00
21930.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
7057.17
-66.40
246.0
247.0
572.0
1238.0
36.0
170.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039099 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Pancreatic ribonuclease
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
Staphylococcus aureus (Gram-positive)
PaperThe transcriptional landscape of the mammalian genome; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15693621;16141072;15489334;25075772 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15693621/
RECORD: Rec_0157630 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Pancreatic ribonuclease
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
E. faecium (Gram-positive)
PaperThe transcriptional landscape of the mammalian genome; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15693621;16141072;15489334;25075772 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15693621/
RECORD: Rec_0173710 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Pancreatic ribonuclease
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
Micrococcus luteus (Gram-negative)
PaperThe transcriptional landscape of the mammalian genome; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15693621;16141072;15489334;25075772 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15693621/
RECORD: Rec_0270405 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Pancreatic ribonuclease
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
Enterococcus faecalis (Gram-positive)
PaperThe transcriptional landscape of the mammalian genome; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15693621;16141072;15489334;25075772 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15693621/
RECORD: Rec_0324866 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Pancreatic ribonuclease
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
Pseudomonas aeruginosa (Gram-negative)
PaperThe transcriptional landscape of the mammalian genome; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15693621;16141072;15489334;25075772 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15693621/
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