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MYP_096774
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Basic Information
Cter G
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anthelminthic
Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C133H215N35O41S6
Standard
Sequence
GLPCGESCVFIPCITTVVGCSCKNKVCYNN
Physicochemical Analysis
3152.73 Da
7.77
0.70
0.40
0.0233
0.56
0.34
0.22
35.46
77.67
0.0667
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1209.40
-14.61
46.0
48.0
98.0
215.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0297796 VERIFIED: NO
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21194241 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21194241/
RECORD: Rec_0322081 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
43366
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
40 μM
MIC
PaperBactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra.
RECORD: Rec_0339637 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
43366
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
>160 μM
MIC
PaperBactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra.
RECORD: Rec_0370664 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Antifungal Insecticidal Hemolytic Nematocidal Anthelmintic Anti-Gram-negative
Pseudomonas aeruginosa
0.625 μM
MIC
PaperPubMed PMID 28669767 | PubMed PMID 21194240 PMID28669767;21194240 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0376014 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Antifungal Insecticidal Hemolytic Nematocidal Anthelmintic Anti-Gram-negative
Pseudomonas aeruginosa
160 μM
MIC
PaperPubMed PMID 28669767 | PubMed PMID 21194240 PMID28669767;21194240 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
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