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MYP_096763
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Basic Information
Cyclotide vibi-C (Plant defensin)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C125H188N34O40S6
Standard
Sequence
GLPVCGETCAFGSCYTPGCSCSWPVCTRN
Physicochemical Analysis
2999.42 Da
5.96
-0.30
-0.59
-0.0103
0.25
0.26
0.19
62.03
36.90
0.1034
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1151.44
-15.99
46.0
46.0
85.0
205.0
7.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018822 VERIFIED: YES
Provenance & Taxonomy
Viola biflora [Plant]
Defensin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-19; 9-21; 14-26
Bio-Activity Profile
Cytotoxic
PaperPubMed PMID: 18191970 PMID18191970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18191970/
RECORD: Rec_0037806 VERIFIED: YES
Provenance & Taxonomy
Viola biflora [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperThe alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity.
RECORD: Rec_0055611 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant],Viola biflora [Plant]
Cyclotide
214053
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Cytotoxic
PMID18191970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18191970/
RECORD: Rec_0272975 VERIFIED: NO
Provenance & Taxonomy
Viola biflora [Plant]; Viola tricolor [Plant]
Cyclotide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
5-19; 9-21; 14-26
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0324746 VERIFIED: NO
Provenance & Taxonomy
Viola biflora [Plant]
Cyclotide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID18191970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18191970/
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