Peptide Database

Peptide NamegB122Δ1-6

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC51H63N9O13

DescriptionStandard

        TFGGGYVYF
    

Molecular Weight1010.10 Da

Isoelectric Point (pI)5.18

Net Charge (pH 7.0)-0.60

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0671

GRAVY Index0.59

Hydrophobic Moment 0.14

Boman Index0.60

Instability Index32.21

Aliphatic Index 32.22

Aromaticity 0.4444

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 356.81

LogP -1.41

H-bond Donors 13.0

H-bond Acceptors 13.0

Rotatable Bonds 27.0

Heavy Atoms 73.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218283 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHerpes simplex virus type 1(HSV-1):comprehensive antiviral activity

Activity100 μM

MethodEC50

RECORD: Rec_0226115 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0357369 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtein-derived synthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-HSV Entry inhibition

TargetHerpes simplex virus type 1 (HSV-1)

Activity100 μM

MethodEC50

Half-LifeMammalian: 7.2 h; Yeast: >20 h; E. coli: >10 h

PaperMultiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection. | Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR. | Antimicrob Agents Chemother. 2009 Mar;53(3):987-96. | DOI:10.1128/AAC.00793-08 | PMID:19104014 PMID19104014 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19104014/