Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length200 amino acids

Chemical FormulaC1030H1549N231O309S7

DescriptionStandard

        QIDDLAEVDYSLSSFPAVFQPFIDLDLKGIVFPAGNYTDSPYVAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEESNLVTHLFSLFYFFIQTCSYFSINTEIFSSIIPEVAKYSVTPYPVMLKLMSTEVPVISLQQDSFTVEIRGSVEVLAILPDSTTRSLFTLNVAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight22336.13 Da

Isoelectric Point (pI)4.07

Net Charge (pH 7.0)-13.15

Net Charge (pH 7.4) -13.48

Charge Density (pH 7.0) -0.0658

GRAVY Index0.37

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index45.82

Aliphatic Index 95.55

Aromaticity 0.1500

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8572.18

LogP -103.54

H-bond Donors 295.0

H-bond Acceptors 304.0

Rotatable Bonds 710.0

Heavy Atoms 1577.0

Ring Count 41.0

Amide Bonds 215.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0170109 VERIFIED: NO

Provenance & Taxonomy

OrganismChloropsis cyanopogon [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria