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MYP_096750
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Basic Information
Mastoparan-L
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
14 amino acids
C70H130N18O16
Standard
Sequence
INLKALAALAKKIL
Physicochemical Analysis
1479.89 Da
10.30
2.76
2.55
0.1969
1.16
0.58
0.30
10.91
195.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
562.77
-1.68
19.0
19.0
53.0
104.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0118055 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mastoparan analogue 9 : (A. baumannii strain CR17
2.6 μM
MIC
PMID26114811 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26114811/
RECORD: Rec_0127581 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperChem Pharm Bull (Tokyo). 1979 Aug;27(8):1942-4. | http://www.ncbi.nlm.nih.gov/pubmed/540362 PMID540362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/540362/
RECORD: Rec_0155633 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
25 μM
MIC
PMID27423268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27423268/
RECORD: Rec_0169989 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli (BL21)
2 μM
MIC
PMID31411881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31411881/
RECORD: Rec_0189943 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
A. baumannii strain CR86
21.6 μM
MIC
PMID26114809 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26114809/
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