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MYP_096750
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Basic Information
Mastoparan-L
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
14 amino acids
C70H130N18O16
Standard
Sequence
INLKALAALAKKIL
Physicochemical Analysis
1479.89 Da
10.30
2.76
2.55
0.1969
1.16
0.58
0.30
10.91
195.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
562.77
-1.68
19.0
19.0
53.0
104.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042110 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mastoparan analogue 9 : (A. baumannii strain CR17
21 μM
MIC
PMID26114811 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26114811/
RECORD: Rec_0053889 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperMoerman L., Bosteels S., Noppe W., Willems J., Clynen E., Schoofs L., Thevissen K., Tytgat J., Van Eldere J., Van Der Walt J., Verdonck F.. Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. Eur. J. Biochem., 269, 4799-4810, 2002.
RECORD: Rec_0054103 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12354111/ PMID12354111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
RECORD: Rec_0056916 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 57.1%, E 0.0%, T 21.4%, C 21.4% [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
None
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0065948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
A. baumannii strain CR17
2.7 μM
MIC
PMID26114810 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26114810/
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