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MYP_096750
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Basic Information
Mastoparan-L
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
14 amino acids
C70H130N18O16
Standard
Sequence
INLKALAALAKKIL
Physicochemical Analysis
1479.89 Da
10.30
2.76
2.55
0.1969
1.16
0.58
0.30
10.91
195.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
562.77
-1.68
19.0
19.0
53.0
104.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0406709 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
C-terminal amidation
Bio-Activity Profile
Hemolytic
PaperMoerman L., Bosteels S., Noppe W., Willems J., Clynen E., Schoofs L., Thevissen K., Tytgat J., Van Eldere J., Van Der Walt J., Verdonck F.. Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. Eur. J. Biochem., 269, 4799-4810, 2002. PMID12354111
RECORD: Rec_0409695 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (ATCC 12600)
8 μM
MIC
PMID31411881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31411881/
RECORD: Rec_0411767 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
TAM
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Rhodamine conjugation
N-terminal modification: Rhodamine conjugation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID22148546 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0418143 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Structure & Mods
amphipathic alpha-helical linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
rat red blood cells
PMID27423268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27423268/
RECORD: Rec_0420070 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Enterococcus faecalis ATCC 12953
~10 μM
MIC
PaperA new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii PMID540362
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