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MYP_096750
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Basic Information
Mastoparan-L
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
14 amino acids
C70H130N18O16
Standard
Sequence
INLKALAALAKKIL
Physicochemical Analysis
1479.89 Da
10.30
2.76
2.55
0.1969
1.16
0.58
0.30
10.91
195.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
562.77
-1.68
19.0
19.0
53.0
104.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0278268 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E. cloacae (clinical isolate 1383251)
32 μM
MIC
PMID31411881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31411881/
RECORD: Rec_0283923 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
A. baumannii strain Ab113
43.3 μM
MIC
PMID26114809 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26114809/
RECORD: Rec_0286107 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PA14
8 μM
MIC
PMID31411881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31411881/
RECORD: Rec_0287072 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Bacillus subtilis ATCC 6633
~20 μM
MIC
PaperA new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii
RECORD: Rec_0287396 VERIFIED: NO
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
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