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MYP_096750
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Basic Information
Mastoparan-L
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
14 amino acids
C70H130N18O16
Standard
Sequence
INLKALAALAKKIL
Physicochemical Analysis
1479.89 Da
10.30
2.76
2.55
0.1969
1.16
0.58
0.30
10.91
195.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
562.77
-1.68
19.0
19.0
53.0
104.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001077 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus ATCC 29213 or MRSA
10-20 μM
MIC
PaperA new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii
RECORD: Rec_0005545 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
A. baumannii strain Ab113
173 μM
MIC
PMID26114809 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26114809/
RECORD: Rec_0005965 VERIFIED: YES
Provenance & Taxonomy
Vespula lewisii [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (ATCC 25923)
32 μM
MIC
PMID31411881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31411881/
RECORD: Rec_0010725 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Inverso
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23585561 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23585561/
RECORD: Rec_0019924 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
A. baumannii strain Ab113
2.7 μM
MIC
PMID26114810 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26114810/
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