Peptide Database

Peptide NameConotoxin Lt3.5

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC51H87N15O19S6

DescriptionStandard

        CCKVQCESCTPCC
    

Molecular Weight1406.72 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0229

GRAVY Index0.40

Hydrophobic Moment 0.15

Boman Index-0.03

Instability Index56.07

Aliphatic Index 22.31

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 550.60

LogP -8.41

H-bond Donors 24.0

H-bond Acceptors 25.0

Rotatable Bonds 43.0

Heavy Atoms 91.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004743 VERIFIED: NO

Provenance & Taxonomy

OrganismConus litteratus [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-13; 2-9; 6-12

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0317555 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 30.8%, E 0.0%, T 38.5%, C 30.8% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic