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MYP_096723
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Basic Information
Deserticolin-1 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
19 amino acids
C93H151N23O26
Standard
Sequence
GLADFLNKAVGKVVDFVKS
Physicochemical Analysis
2007.33 Da
8.50
0.76
0.55
0.0400
0.52
0.64
0.20
-13.30
112.63
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
803.10
-6.17
27.0
27.0
68.0
142.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0378610 VERIFIED: YES
Provenance & Taxonomy
Crinia deserticola [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 35218
>100 μM
IC50
PaperDisulfide-containing peptides from the glandular skin secretions of froglets of the genus Crinia: Structure, activity and evolutionary trends.
RECORD: Rec_0382832 VERIFIED: YES
Provenance & Taxonomy
Crinia deserticola [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactococcus lactis
25 μM
MIC
PMID18601958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18601958/
RECORD: Rec_0409305 VERIFIED: NO
Provenance & Taxonomy
Crinia deserticola [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal
Bacillus cereus, Enterobacter cloacae, Escherichia coli, Enterococcus faecalis, Listeria innocua, Lactococcus lactis, Micrococcus luteus, Staphylococcus aureus, S.uberis
Qualitative functional evidence
PMID18601958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18601958/; https://www.uniprot.org/uniprotkb/P86136/entry; https://bblserver.org.in/ampdb/
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