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MYP_096720
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Basic Information
XPF-AN1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C121H205N33O33S
Standard
Sequence
GWASKIGQTLGKMAKVGLQELIQPK
Physicochemical Analysis
2682.19 Da
10.00
2.76
2.55
0.1104
-0.20
0.69
0.09
41.36
97.60
0.0400
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1079.83
-8.98
36.0
37.0
94.0
188.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029647 VERIFIED: YES
Provenance & Taxonomy
Xenopus andrei [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
50 μM
MIC
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
RECORD: Rec_0037254 VERIFIED: YES
Provenance & Taxonomy
Xenopus andrei [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
RECORD: Rec_0136650 VERIFIED: YES
Provenance & Taxonomy
Xenopus gilli [Animal] [Animal]; Xenopus andrei [Animal] [Animal]; Xenopus wittei [Animal] [Animal]; Xenopus ruwenzoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
80 μM
MIC
RECORD: Rec_0140470 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21740067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21740067/
RECORD: Rec_0192231 VERIFIED: YES
Provenance & Taxonomy
Xenopus andrei [Animal]
XPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
50.0 μM
MIC
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part D 6 (2011) 206-212. Genome duplications within the Xenopodinae do not increase the multiplicity of antimicrobial peptides in Silurana paratropicalis and Xenopus andrei skin secretions
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