Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC383H600N102O105S8

DescriptionStandard

        MRVLFLIFGVLYLLSTVPPARSFIYIDECPSEYYNCRMKCNADEHAIRYCDDWTICCKLKNIEIEKLRRER
    

Molecular Weight8570.00 Da

Isoelectric Point (pI)7.56

Net Charge (pH 7.0)0.54

Net Charge (pH 7.4) 0.16

Charge Density (pH 7.0) 0.0076

GRAVY Index-0.13

Hydrophobic Moment 0.56

Boman Index-0.05

Instability Index64.53

Aliphatic Index 93.38

Aromaticity 0.1268

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3360.37

LogP -22.79

H-bond Donors 125.0

H-bond Acceptors 115.0

Rotatable Bonds 282.0

Heavy Atoms 598.0

Ring Count 14.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0286451 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca nemestrina [Animal]

FamilyDefensin

Tax ID9545

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence