Peptide Database

Peptide NameSodium channel neurotoxin MeuNaTxalpha-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC413H643N117O121S11

DescriptionStandard

        MNYLVMISLALLLMTGVESARDAYIANDRNCVYTCALNPYCDSECKKNGADSGYCQWFGRFGNACWCKNLPDKVPIRIPGECRGR
    

Molecular Weight9535.95 Da

Isoelectric Point (pI)8.13

Net Charge (pH 7.0)1.43

Net Charge (pH 7.4) 1.07

Charge Density (pH 7.0) 0.0168

GRAVY Index-0.18

Hydrophobic Moment 0.54

Boman Index-0.00

Instability Index28.05

Aliphatic Index 72.35

Aromaticity 0.1059

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3845.27

LogP -38.60

H-bond Donors 141.0

H-bond Acceptors 134.0

Rotatable Bonds 308.0

Heavy Atoms 662.0

Ring Count 15.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0406438 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

FamilyLong (4 C-C) scorpion toxin; Sodium channel inhibitor; Alpha subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Toxin Non-hemolytic

TargetNo Target Organism Found