Peptide Database

Peptide NameGlial cell line-derived neurotrophic factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length134 amino acids

Chemical FormulaC633H1042N206O196S8

DescriptionStandard

        SPDKQAAALPRRERNRQAAAASPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCEAAETMYDKILKNLSRSRRLTSDKVGQACCRPVAFDDDLSFLDDSLVYHILRKHSAKRCGCI
    

Molecular Weight14930.83 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)8.67

Net Charge (pH 7.4) 8.17

Charge Density (pH 7.0) 0.0647

GRAVY Index-0.66

Hydrophobic Moment 0.78

Boman Index-0.23

Instability Index59.02

Aliphatic Index 72.91

Aromaticity 0.0522

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6598.29

LogP -79.78

H-bond Donors 243.0

H-bond Acceptors 216.0

Rotatable Bonds 511.0

Heavy Atoms 1043.0

Ring Count 14.0

Amide Bonds 142.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205114 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyTGF-beta family

Tax ID10116; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide41-102; 68-131; 72-133

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Growth factor signaling