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MYP_096627
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Basic Information
Melanotropin alpha (6-13)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
8 amino acids
C50H71N15O9
Standard
Sequence
HFRWGKPV
Physicochemical Analysis
1026.19 Da
11.00
1.85
1.59
0.2308
-0.94
0.58
-0.09
58.46
36.25
0.2500
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
390.62
-1.09
14.0
12.0
29.0
74.0
5.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073604 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse erythrocytes (<1% Hemolysis at <62.5 microM
62.5 μM
Hemolysis
PMID33195893 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33195893/
RECORD: Rec_0144292 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 33591
45.45 μM
MIC
PMID33195893 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33195893/
RECORD: Rec_0169100 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6803044 B1 Evidence URLhttps://patents.google.com/patent/US6803044B1/en PatentUS 6803044 B1
RECORD: Rec_0194858 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPatent US 7244710 B2 Evidence URLhttps://patents.google.com/patent/US7244710B2/en PatentUS 7244710 B2
RECORD: Rec_0284896 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Melanocortin (α-MSH)
9606.0
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV
Herpesvirus, HIV
PaperAlpha-melanocyte-stimulating hormone peptides inhibit HIV-1 expression in chronically infected promonocytic U1 cells and in acutely infected monocytes; Patent: Treatment Of Ophthalmic Infections Using Antimicrobial Peptides PMID11073109 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11073109/ PatentUS 7244710
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