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MYP_096582
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Basic Information
D-lys-CP
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C59H109N13O15
Standard
Sequence
ILGTILGLLKSL
Physicochemical Analysis
1240.57 Da
8.75
0.76
0.55
0.0633
1.82
0.41
0.61
27.12
227.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.90
-1.18
16.0
16.0
43.0
87.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0092833 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0099083 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
K. influenza
128
MIC
PMID28981608 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28981608/
RECORD: Rec_0110739 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
MCD; Protonectin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antiparasitic Anti-Gram-negative Anti-Gram-positive Anticancer Chemotactic Cytotoxic Hemolytic
Bacillus subtilis (Gram-positive)
PMID16129513;21745529;22450985;23836163;30534613;32360153 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16129513/
RECORD: Rec_0113913 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 899701
PMID23836164 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23836164/
RECORD: Rec_0150833 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
4 μM
MIC
PaperStructural and functional characterization of two novel peptide toxins isolated from the venom of the social wasp Polybia paulista
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