Peptide Database

Peptide NameamyE signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory expression optimization

Enzyme / Catalytic activity ▸ Hydrolase ▸ Protease/Peptidase

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC152H236N34O30S

DescriptionStandard

        MFAKRFKTSLLPLFAGFLLLFHLVLAG
    

Molecular Weight3051.77 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)2.59

Net Charge (pH 7.4) 2.32

Charge Density (pH 7.0) 0.0958

GRAVY Index1.35

Hydrophobic Moment 0.47

Boman Index0.48

Instability Index23.27

Aliphatic Index 137.41

Aromaticity 0.1852

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 994.21

LogP -0.32

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 98.0

Heavy Atoms 217.0

Ring Count 7.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392706 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Aminopeptidase (AP) secretion

TargetBacillus subtilis WB600

Activity5.12 U/mL

MethodAminopeptidase activity assay

PaperGuan C, Cui W, Cheng J, et al. Construction of a highly active secretory expression system via an engineered dual promoter and a highly efficient signal peptide in Bacillus subtilis[J]. New Biotechnology, 2016, 33(3): 372-379. PMID26820123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26820123/