Peptide Database

Peptide NameBone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP)]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length227 amino acids

Chemical FormulaC1093H1703N323O338S11

DescriptionStandard

        MKFPLLLALLVGGAFALHLSSEASDSKSPLVDESLPREAEISRPEVEESPPGEQLMSLEEEEEEEEEEGSGSEGALGNEGAVSGQDVTDENLQSPKEEDTTSLMGDSGFKTGRYLLVRRPECFNKAQLVCRSCYRGTLASIHSFSVNFRIQSFVRGINQGQVWIGGRIVGWGRCKRFRWIDGSSWNFAYWAAGQPRRGGGRCVTLCTRGGHWRRSGCGKRRPFICAY
    

Molecular Weight25128.89 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-3.25

Net Charge (pH 7.4) -3.80

Charge Density (pH 7.0) -0.0143

GRAVY Index-0.50

Hydrophobic Moment 0.77

Boman Index-0.07

Instability Index73.27

Aliphatic Index 67.44

Aromaticity 0.0881

Extinction Coeff. Reduced 38960.00

Extinction Coeff. Oxidized 39460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323561 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Lectin Cytolytic Cytotoxic Non-hemolytic