Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC329H530N86O84S9

DescriptionStandard

        MRTLLFLFVLLFFLGPAMNKFLDEKCIRLDGRCSADCKKNEELVGLCHKAQKCCLLLEPCWQK
    

Molecular Weight7322.84 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)2.53

Net Charge (pH 7.4) 2.14

Charge Density (pH 7.0) 0.0401

GRAVY Index0.22

Hydrophobic Moment 0.55

Boman Index0.05

Instability Index35.55

Aliphatic Index 100.63

Aromaticity 0.0952

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2736.17

LogP -16.47

H-bond Donors 100.0

H-bond Acceptors 97.0

Rotatable Bonds 250.0

Heavy Atoms 508.0

Ring Count 10.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353438 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic