Peptide Database

Peptide NameNeurotoxin Hm-2

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC205H296N52O53S7

DescriptionStandard

        GCIPSFGECAWFSGESCCTGICKWVFFTSKFMCRRVWGKD
    

Molecular Weight4561.31 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.41

Charge Density (pH 7.0) 0.0427

GRAVY Index0.20

Hydrophobic Moment 0.44

Boman Index0.15

Instability Index45.41

Aliphatic Index 36.50

Aromaticity 0.2000

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1671.94

LogP -14.04

H-bond Donors 67.0

H-bond Acceptors 62.0

Rotatable Bonds 143.0

Heavy Atoms 317.0

Ring Count 12.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124475 VERIFIED: NO

Provenance & Taxonomy

OrganismHeriaeus melloteei [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-18; 9-22; 17-33

Bio-Activity Profile

Function

Toxin

TargetNav1