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MYP_096494
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Basic Information
Met-enkephalin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral ▸ Anti-HIV
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ opioid neuropeptide precursor family
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide activity ▸ opioid neuropeptide precursor family
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C27H35N5O7S
Standard
Sequence
YGGFM
Physicochemical Analysis
573.66 Da
5.52
-0.24
-0.45
-0.0482
0.52
0.17
0.61
15.70
0.00
0.4000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
199.95
-0.46
7.0
8.0
16.0
40.0
2.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0086286 VERIFIED: YES
Provenance & Taxonomy
Theromyzon tessulatum [Animal]
Opioid
13286
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID7805888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7805888/
RECORD: Rec_0089448 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Enkephalin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
PMID7512741 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7512741/
RECORD: Rec_0093933 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Met-enkephalin
9606
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Anti-HIV
Human immunodeficiency virus 1
Clinical trial
PMID2967309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2967309/
RECORD: Rec_0098052 VERIFIED: YES
Provenance & Taxonomy
Felis catus [Animal]
Met-enkephalin
9685
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Receptor modulation
Experimental: 12.8 minutes; /768 seconds; Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Met-enkephalin (Felis catus): PMID 8719703##3215483 PMID8719703;3215483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8719703/
RECORD: Rec_0107371 VERIFIED: YES
Provenance & Taxonomy
Theromyzon tessulatum [Animal]
Met-enkephalin
13286
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Experimental: 12.8 minutes; /768 seconds; Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Met-enkephalin (Theromyzon tessulatum): PMID 7805888##3215483 PMID7805888;3215483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7805888/
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