Peptide Database

Peptide NameMet-enkephalin

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral ▸ Anti-HIV

Cardiovascular

Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier

Delivery / Targeting ▸ Drug delivery vehicle

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Analgesic/opioid activity ▸ opioid neuropeptide precursor family

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling

Neurological / Signaling ▸ Neuropeptide activity ▸ opioid neuropeptide precursor family

Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC27H35N5O7S

DescriptionStandard

        YGGFM
    

Molecular Weight573.66 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0482

GRAVY Index0.52

Hydrophobic Moment 0.17

Boman Index0.61

Instability Index15.70

Aliphatic Index 0.00

Aromaticity 0.4000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 199.95

LogP -0.46

H-bond Donors 7.0

H-bond Acceptors 8.0

Rotatable Bonds 16.0

Heavy Atoms 40.0

Ring Count 2.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425696 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyMet-enkephalin

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeExperimental: 12.8 minutes; /768 seconds; Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min

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