Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length169 amino acids

Chemical FormulaC808H1311N235O240S18

DescriptionStandard

        MRAGGVLTSLRGRAELSWRQMRASRTAATTATLKVFISGGLNCSNWFRALTLVQEKSEELTRVTCTRVKARNQLEQFSPPEMKTFSVAVVAAVLLALICLQESSALPLSELEDVEVPVMDDNGAAVYEEMPVDSWKMPYTNRHKRSPKRCKFCCNCCPGMSGCGVCCRF
    

Molecular Weight18734.65 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)5.51

Net Charge (pH 7.4) 5.04

Charge Density (pH 7.0) 0.0326

GRAVY Index-0.09

Hydrophobic Moment 0.61

Boman Index-0.02

Instability Index57.70

Aliphatic Index 76.15

Aromaticity 0.0651

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 20105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7649.61

LogP -82.81

H-bond Donors 281.0

H-bond Acceptors 265.0

Rotatable Bonds 620.0

Heavy Atoms 1301.0

Ring Count 23.0

Amide Bonds 179.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0298997 VERIFIED: NO

Provenance & Taxonomy

OrganismTakifugu rubripes [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal