‹ ›
MYP_096465
← PREVIOUS NEXT → BACK
Basic Information
Brevinin-1PRa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
24 amino acids
C122H211N27O29S2
Standard
Sequence
FLPVLTGLTPSIVPKLVCLLTKKC
Physicochemical Analysis
2584.27 Da
9.39
2.74
2.50
0.1141
1.16
0.52
0.36
39.10
150.00
0.0417
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
865.23
-3.39
31.0
34.0
81.0
180.0
4.0
23.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0041225 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Anti-Gram-positive
Staphylococcus aureus
50 μM
MIC
RECORD: Rec_0089645 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
69834
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
100 μM
MIC
PaperHost defense peptides in skin secretions of the Oregon spotted frog Ranapretiosa: implications for species resistance to chytridiomycosis
RECORD: Rec_0094239 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
50 μM
MIC
PMID21295070 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21295070/
RECORD: Rec_0101645 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
100 μM
MIC
PaperPubMed PMID: 15003829 | PubMed PMID: 21295070 PMID15003829;21295070 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15003829/
RECORD: Rec_0112784 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human erythrocytes
150 μM
LC50
PaperPubMed PMID: 15003829 | PubMed PMID: 21295070 PMID15003829;21295070 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15003829/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 2 of 5